As the low frequency of GG genotype, the CG and GG genotype were combined for analysis in the dominant model, although an increasing trend can also be observed in HCC and LC groups compared with CHB group regarding the frequency of genotype with G allele (39.2% versus 34.0% versus 33.6% resp.), the statistical level was not significant, indicating that there was no significant association between rs1800796 polymorphism and the progression of chronic HBV infection in all subjects. 3.3.
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Rather than Rs1800796 polymorphism, expression of interleukin-6 is associated with disease progression of chronic HBV infection in a Chinese Han population.
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The sentences
Second, although the highly significant association between IL-6 and susceptibility to disease progression of chronic HBV infection derives from a prior hypothesis with substantially biological basis, our initial findings should be independently verified in large size of the Chinese population and other different ancestry.