Cryptococcus neoformans ex vivo capsule size is associated with intracranial pressure and host immune response in HIV-associated cryptococcal meningitis.

By stratifying the cohort into OP categories, it became apparent that this effect was particularly driven by the patients with extremely high OP >40 cm H 2 O (Figure 1 ). The correlation between total cell diameter and baseline opening OP was of borderline significance ( r = 0.18, P = .05).

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