High levels of oncomiR-21 contribute to the senescence-induced growth arrest in normal human cells and its knock-down increases the replicative lifespan.

Aging Cell · 2013 · PMC3864473 · PMID 23496142

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highly significantno p-value reported

Using MTT assay as a measure of cell numbers, we observed a highly significant reduction by more than 35% as compared to control ( Fig. 2 C).

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