Mitochondrial IF₁ preserves cristae structure to limit apoptotic cell death signaling.

Cell Cycle · 2013 · PMC3865037 · PMID 23907134

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Interestingly, IF 1 is strongly overexpressed in many human tumors, suggesting that the suppression of apoptotic cell death by this small protein may prove highly significant in the metabolic and structural adaptations associated with tumor development.

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