Epigenetics meets metabolomics: an epigenome-wide association study with blood serum metabolic traits.

Only few highly significant loci- and two loci group-specific CpG–metabotype associations remain after removal of the confounding genetic effects After exclusion of the inflated association signals and confounding genetic effects, only seven distinct loci ( UGT2B15, TXNIP, DHCR24, MYO5C, ABCG1, SLC25A22 and CPT1A ) and two loci groups (named STEROIDS —comprising five loci—and VINYLPHENOL —comprising eight loci—by reference to the associated traits) remain (Table 2 ).

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