Potential reduction of contralateral second breast-cancer risks by prophylactic mammary irradiation: validation in a breast-cancer-prone mouse model.

Although here statistical significance was not reached for any dosage group alone, the Poisson trend statistic [ 32 ] suggested a highly significant (p = 0.00012) decreasing trend in tumor incidence rate over the dose range from 4 Gy to 16 Gy.

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