Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway.

Mol Psychiatry · 2014 · PMC3873038 · PMID 23164821

Europe PMC DOI

hedged sentence

0.0027

closest p · 0.1× alpha

0.0027

boldest claim

The sentences

highly significantP <0.0027actually significant

Interrogating a publically available whole-genome expression data set from DS brain, 43 we found highly significant enrichment of Dkk1-responsive genes ( P <0.0027), adding further to the evidence that this gene signature is driven by Aβ.

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