Risk factors associated with medial tibial stress syndrome in runners: a systematic review and meta-analysis.

Open Access J Sports Med · 2013 · PMC3873798 · PMID 24379729

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highly significantno p-value reported

51 Prior use of orthotics was found to be a highly significant risk factor for developing MTSS.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.