Whi3, an S. cerevisiae RNA-binding protein, is a component of stress granules that regulates levels of its target mRNAs.

At both 30°C and 46°C, all Whi3 target mRNAs, but not APE3 , displayed greater abundance in whi3 Δ than in wild-type cells ( Figure 6B ), and this effect was highly significant ( Figure 6C , p<0.001, 2-way ANOVA).

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