Comparative efficacy of 5flourouracil/calcium leucovorine versus 5flourouracil/calcium leucovorine plus oxaliplatin in the adjuvant treatment of colonic carcinoma in Kashmir.

To summarize: The clinical features, risk factors, familial predisposition and presenting symptoms of patients in this study are similar to patients in other parts of the world There is no added survival advantage by adding oxaliplatin to 5FU and CLV in the adjuvant treatment of colonic carcinoma Hematological and neurological toxicities were more common in the oxaliplatin-based regimen GI toxicity is more common in the Mayo clinic regimen Colonic carcinoma is a common malignancy in our population and has shown an increasing trend in younger patients.

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