Barely Significant
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Physical weight loading induces expression of tryptophan hydroxylase 2 in the brain stem.

PLoS One · 2014 · PMC3885668 · PMID 24416346

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a decreasing trendno p-value reported
Although not significant (p>0.05), knee loading at 1 N showed a decreasing trend of NGFß in the femur and cartilage as compared to the control, consistent with the previous report [12] .

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