This finding is likely to be significant in the understanding of T1D, as Th17 differentiated CD4+ T lymphocytes are incapable of mediating T1D in the inducible NOD.scid model prior to acquisition of the IFN γ effector function [ 36 , 37 ].
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This finding is likely to be significant in the understanding of T1D, as Th17 differentiated CD4+ T lymphocytes are incapable of mediating T1D in the inducible NOD.scid model prior to acquisition of the IFN γ effector function [ 36 , 37 ].