HIF-2: the missing link between obesity and cardiomyopathy.

J Am Heart Assoc · 2013 · PMC3886772 · PMID 24342999

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15 Deletion of Vhl in adipocytes led to highly significant increases in the expression of inflammatory cytokines and chemokines, such as Il1b , Il6 , Tnf , Ccl2 , Ccl3 , Ccl7 , and Ccl8 , indicating that sustained HIF activation causes strong adipose inflammation.

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