In stratified analysis, carriage of at least one NLRP3 rs35829419 variant allele conferred a 2.5-fold increased risk for pathological interstitial lung fibrosis (OR 2.44, 95% CI 0.97 to 6.14), although this association was only borderline significant.
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Genes involved in innate immunity associated with asbestos-related fibrotic changes.
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