highly significantp-value = 2×10 -5
Strikingly, ontological analysis established that six of the 17 CIS genes have transcription factor activity ( Nfia , Tead1 , Tgif2 , Nfib , Myt1l and L3mbtl4 ), a highly significant excess relative to expectation (FDR corrected p-value = 2×10 -5 ).