Global state measures of the dentate gyrus gene expression system predict antidepressant-sensitive behaviors.

Regression analyses indicated that for both dentate regions and for both behavioral measures there were highly significant correlations between system state (PCA1) and behavior ( Figure 3: Immobility in the FST – ventral: Spearman r = −0.63, p = 0.004***, dorsal: Spearman r = −0.63, p = 0.004***; Latency to eat in the NSF – ventral: Spearman r = −0.79, p<0.001***, dorsal: Spearman r = −0.81, p<0.001***).

also in 132,142 other papers