Beta-catenin is vital for the integrity of mouse embryonic stem cells.

PLoS One · 2014 · PMC3897734 · PMID 24466203

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highly significantno p-value reported

All three genes appear highly significant induced in ARβ1 ES cells after ablation of β-catenin by administration of 4-OHT ( Fig. 3C ) supporting our finding that ablation of β-catenin in ES cells leads to an onset of apoptosis as early cellular response.

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