Receptor for Advanced Glycation Endproducts (RAGE), Its Ligands, and Soluble RAGE: Potential Biomarkers for Diagnosis and Therapeutic Targets for Human Renal Diseases.

Genomics Inform · 2013 · PMC3897850 · PMID 24465234

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Interaction between RAGE and its ligands changes renal cellular processes, including inflammation, proliferation, and migration, and they are highly significant processes to keep the normal function of kidneys; therefore, dysregulation of RAGE or its ligand concentrations might give fatal effects, leading to the development and pathogenesis of renal diseases.

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