highly significantp = 0.008
We found a highly significant 25% increase in 5-HT tissue levels in the PFC (WT:1.37 ± 0.07 pmol/mg, Nogo-A: 1.71 ± 0.08 pmol/mg; t 22 = 2.895, p = 0.008) while the metabolite 5-Hydroxyindoleacetic acid (5-HIAA) was not altered.