siRNA screening identifies differences in the Fanconi anemia pathway in BALB/c-Trp53+/- with susceptibility versus C57BL/6-Trp53+/- mice with resistance to mammary tumors.

Gene-specific differences reaching statistical significance ( P -values <0.05 for 39 genes, see Supplementary Table 1 ) were validated in a rescreen, enabling selection of 25 hits with highly significant differences ( P -values <0.001, Figure 1c and Table 1 ).

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