highly significantP< 0.001
There was a highly significant difference between the Kaplan–Meier curves for HPV-positive OPSCC DSS according to TIL levels ( P< 0.001; Figure 1E ); patients with HPV-positive/TIL low tumours showed similar DSS to HPV-negative patients ( Figure 1E ) with an adjusted HR of 1.01 ( P =0.98; Table 2A ).