High risk population isolate reveals low frequency variants predisposing to intracranial aneurysms.

PLoS Genet · 2014 · PMC3907358 · PMID 24497844

Europe PMC DOI

hedged sentence

0.0000

closest p · 0.0× alpha

0.0000

boldest claim

The sentences

highly significantp = 1.05×10 −7actually significant

They were highly significant in the Dutch sample (rs12472355; OR, 1.39, CI 1.23–1.57, p = 1.05×10 −7 and rs919433; OR 1.43, CI 1.26–1.61, p 9.77×10 −9 ), and in the meta-analysis of all three samples they reached genome-wide significance ( Table 2 ).

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