The Melody® valve and Ensemble® delivery system for transcatheter pulmonary valve replacement.

Ann N Y Acad Sci · 2013 · PMC3910161 · PMID 23834411

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may be significantno p-value reported

If a patient waits too long before relieving the RVOT dysfunction, there may be significant and irreversible damage to the RV that can have an important impact on long-term prognosis.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.