Although the positive association between the carrier frequency of DRB1*15:01 and SLE failed to reach significance in this set ( P c = 0.0705, odds ratio [OR] 1.76, 95% confidence interval [CI] 1.22–2.53, Table 1 ), a significant protective association was found for DRB1*13:02 and SLE ( P c = 0.0123, OR 0.42, 95% CI 0.26–0.68).
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Human leukocyte antigens and systemic lupus erythematosus: a protective role for the HLA-DR6 alleles DRB1*13:02 and *14:03.
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The sentences
In this case, a significant positive association was found for DRB1*15:01 and SLE ( P c = 8.90×10 −6 , OR 2.47, 95% CI 1.75–3.49) and it was the protective association with DRB1*13:02 which just failed to achieve significance ( P c = 0.0646, OR 0.54, 95% CI 0.36–0.80).