A structural homology search using the DALI server (Holm and Rosenstrom, 2010 ) was performed which resulted in the identification of domain 2 of SF1B helicases as TSA's closest structural homologue: the RecD subunit of the RecBCD helicase ranked first with a Z-score of 8.9 (a highly significant score), followed by other SF1B helicase structures.
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Structure of a translocation signal domain mediating conjugative transfer by type IV secretion systems.
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