Short-term treatment with a gonadotropin-releasing hormone antagonist, cetrorelix, in rheumatoid arthritis (AGRA): a randomized, double-blind, placebo-controlled study.

Scand J Rheumatol · 2014 · PMC3913106 · PMID 24182325

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highly significantno p-value reported

Although the exact mechanisms are unknown, the highly significant association between changes in LH, a surrogate marker for GnRH, and TNF-α suggests there is a close relationship between endocrinological and immunological responsiveness to GnRH.

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