The Leishmania major BBSome subunit BBS1 is essential for parasite virulence in the mammalian host.

Mol Microbiol · 2013 · PMC3916885 · PMID 23998526

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highly significantno p-value reported

major parasites compared with the BBS1 mutant lines, with a highly significant difference in lesion size by 48 days onwards (Fig. 3 A).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.