highly significantp<10 −13
Our risk score analysis using the sum of all 54 (both genotyped and well imputed) GWAS-significant risk alleles as a predictor of T2D risk in the Singapore Chinese Health Study population, while highly significant statistically (p<10 −13 ), showed per-allele ORs that are smaller on average (1.05) than the mean (1.16) of the published ORs for these alleles or of the mean (1.07) of the single SNP ORs estimated in this study.