Role of IL-9 and STATs in hematological malignancies (Review).

Oncol Lett · 2014 · PMC3919939 · PMID 24520283

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highly significantno p-value reported

Ctr9 is a subunit of the Paf1 complex The STAT3-Ctr9 interaction is highly significant for pluripotency of mESCs since Ctr9 indirectly induces multiple histone modifications, including trimethylation of Lys4 and Lys36, dimethylation of Lys79 on histone H3 and ubiquitination of histone H2B, all of which are important for gene activation ( 53 ).

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likely to be significantno p-value reported

STAT6 is likely to be significant in determining the nature of genes that are regulated by STAT6 in these tissues.

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