We speculate that this xapA-mediated NAD + salvage pathway might be significant in some bacteria lacking NAD + de novo and NAD + salvage pathway I or II , to not only use nicotinamide riboside, but also nicotinamide as precursors to synthesize NAD + .
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New function for Escherichia coli xanthosine phophorylase (xapA): genetic and biochemical evidences on its participation in NAD(+) salvage from nicotinamide.
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