Similar to spironolactone, oxymatrine is protective in aldosterone-induced cardiomyocyte injury via inhibition of calpain and apoptosis-inducing factor signaling.

PLoS One · 2014 · PMC3923837 · PMID 24551180

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extraordinarily significantno p-value reported

Between-group comparisons were performed by using t-test, statistical significance was set at P<0.05, P<0.01 was considered extraordinarily significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.