Invasive lobular carcinoma of the breast: long-term prognostic value of Ki67 and histological grade, alone and in combination with estrogen receptor.

When the three components of histological grade were analyzed separately by log-rank tests for trend, we found significant differences in BCM between the three different mitotic scores ( p < 0.001), borderline significance between the three pleomorphism groups ( p = 0.04) and non-significant differences for tubule formation ( p = 0.70).

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