Barely Significant
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Prospective screening of family members with moyamoya disease patients.

PLoS One · 2014 · PMC3929504 · PMID 24586386

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may be significantno p-value reported
Because the financial cost of routine screening may be significant, TCD is a cost effective choice.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.