highly significantP = 5×10 −18
All three endogenous miRNAs showed positive and highly significant correlations with the spike-in control (miR-16: r = 0.691 and P = 5×10 −18 , miR-31 r = 0.734 and P = 3.2×10 −21 , miR-223 r = 0.637 and P = 8.5×10 −15 ).