O-hexadecyl-dextran entrapped berberine nanoparticles abrogate high glucose stress induced apoptosis in primary rat hepatocytes.

In co-treatment, BC-HDD NPs showed only 4.9% cells in early apoptosis, 0.9% in late apoptosis, 0.8% cells undergoing necrosis and remaining 93.4% cells were found to be viable confirming highly significant prevention of cytotoxicity due to high glucose stress.

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