Disease mutations in the prion-like domains of hnRNPA1 and hnRNPA2/B1 introduce potent steric zippers that drive excess RNP granule assembly.

Rare Dis · 2013 · PMC3932941 · PMID 25002999

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21 The introduction of additional potent steric zipper motifs by the disease-causing mutations in a PrLD is likely to be significant for two reasons.

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