This had borderline significance in the sensitivity analysis per independent read; median duration of response was 3.9 and 5.0 months with PFE + CIL2W and PFE alone, respectively (HR versus PFE alone: 1.92 [95% CI 0.99–3.74]; P = 0.053).
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Cisplatin, 5-fluorouracil, and cetuximab (PFE) with or without cilengitide in recurrent/metastatic squamous cell carcinoma of the head and neck: results of the randomized phase I/II ADVANTAGE trial (phase II part).
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