CXCR4 inhibition ameliorates severe obliterative pulmonary hypertension and accumulation of C-kit⁺ cells in rats.

PLoS One · 2014 · PMC3933653 · PMID 24587052

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a small trendno p-value reported

The accumulation of vWF + CXCR4 + cells was not significantly reduced by AMD3100 AMD3100 treatment reduced the total number of CXCR4 + cells and CXCR4 + α-SMA + per vessel in the pulmonary arteries of SuHx animals, but there was only a small trend towards reduced number of CXCR4 + vWF + cells after AMD3100 treatment ( Figure 9A-C ).

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