Effectiveness of tigecycline-based versus colistin- based therapy for treatment of pneumonia caused by multidrug-resistant Acinetobacter baumannii in a critical setting: a matched cohort analysis.

In our study we showed borderline significant excess nephrotoxicity of 7.1% of the colistin group compared to tigecycline group ( P = .05) for the baseline characteristic comparable cohorts.

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Since there may be significant baseline characteristic differences between the colistin and tigecycline groups, we used propensity score matching to balance the baseline predictors for colistin or tigecycline use and mortality [ 23 ].

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