Do randomized clinical trials with inadequate blinding report enhanced placebo effects for intervention groups and nocebo effects for placebo groups?

Syst Rev · 2014 · PMC3939643 · PMID 24555576

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a small trendno p-value reported

Our study found a small trend for unblinding in randomized clinical trials to underestimate placebo effects (creating a nocebo effect) and no evidence for the overestimation for intervention effects (enhanced placebo effects).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.