Barely Significant
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Strong genome-wide selection early in the evolution of Prochlorococcus resulted in a reduced genome through the loss of a large number of small effect genes.

PLoS One · 2014 · PMC3940434 · PMID 24594762

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The sentences

highly significantP- value<10 −5actually significant
In particular, the differences are highly significant on branch #1 and branch #2 during the genome reduction period (Student's t-test, P- value<10 −5 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.