The implication of GST polymorphisms may be significant as studies suggest that that loss of mu, pi and theta GST genes increase susceptibility to inflammatory diseases, and a genetic deficiency of GSTM1 is associated with increased susceptibility to ozone-related asthma [ 61 ] and to susceptibility to AFB1-mediated damage to human liver cells [ 62 ].
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Deficient glutathione in the pathophysiology of mycotoxin-related illness.
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