Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion.

PLoS Genet · 2014 · PMC3945174 · PMID 24603685

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borderline significantno p-value reported

While overexpression of Cdkn1a and Pde7b resulted in increased glucagon release at 1 mM glucose compared to control transfected α-cells, Sept9 overexpression led to a borderline significant increase in glucagon secretion ( Figure S3D and Figure 4L ).

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