Attenuation of hedgehog acyltransferase-catalyzed sonic Hedgehog palmitoylation causes reduced signaling, proliferation and invasiveness of human carcinoma cells.

PLoS One · 2014 · PMC3946499 · PMID 24608521

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did not quite reach statistical significanceno p-value reported

HEK293a-Shh cells treated with Hhat-#2 siRNA co-cultured with C3H10T1/2 cells (ratio 1∶2) for 2 days during day 2–4 of KD, resulted in a C3H10T1/2 response decrease of 32±10% compared to non-targeting siRNA, but this did not quite reach statistical significance.

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