Screen of whole blood responses to flagellin identifies TLR5 variation associated with outcome in melioidosis.

Genes Immun · 2014 · PMC3948086 · PMID 24285178

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may be significantno p-value reported

Differential linkage disequilibrium of variants with TLR5 1846T>C across populations In light of the evidence in favour of selection for TLR5 1846T>C in Yorubans 19 , but our inability to conclusively determine a clinical effect of TLR5 1846T>C independent of TLR5 1174C>T in Thais, we hypothesized that there may be significant population-level differences in LD structure in TLR5 .

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