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Trends in the prevalences of congenital anomalies and age at motherhood in a Southern European region: a population-based study.

BMJ Open · 2014 · PMC3948639 · PMID 24589823

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an increasing trendno p-value reported
With marginal statistical significance, the results point at an increasing trend in total diagnosed chromosomal anomalies, but a decreasing one in prevalences at birth.

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