Foveal morphology affects self-perceived visual function and treatment response in neovascular age-related macular degeneration: a cohort study.

For example, clinically meaningful decrease at 12 months is almost significantly associated with an interrupted IS/OS line (OR 5.1, p = 0.07); therefore, future studies should consider larger sample sizes when investigating clinically meaningful changes, as anti-VEGF treatment may be able to preserve the self-perceived visual function in the majority of patients with neovascular AMD.

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