Modulation of p25 and inflammatory pathways by fisetin maintains cognitive function in Alzheimer's disease transgenic mice.

Aging Cell · 2014 · PMC3954948 · PMID 24341874

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highly significantno p-value reported

While fisetin did not significantly alter p35 levels in the hippocampi of the AD mice, it did prevent the highly significant increase in p25 levels in AD mice and greatly reduced the p25/p35 ratio in both wild-type and AD mice (Fig. 2C ).

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