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Therapeutic implications of estrogen for cerebral vasospasm and delayed cerebral ischemia induced by aneurysmal subarachnoid hemorrhage.

Biomed Res Int · 2014 · PMC3958795 · PMID 24724095

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may be significantno p-value reported
However, the potential systemic adverse effects of estrogen on patients, especially those with preexisting medical comorbidities, may be significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.