It remains unclear whether our results reflect the limitations described above or to an actual lack of difference in binding phenotypes for parasites from HbAA and HbAS children – especially since parasites from HbAS children trended towards increased binding to MVECs, but failed to reach significance.
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Ex-vivo cytoadherence phenotypes of Plasmodium falciparum strains from Malian children with hemoglobins A, S, and C.
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